Mankind’s Weapon Against Covid-19 — RT World News

As the infection rate rises again, scientists around the world are scrambling to fight the danger, offering new treatments and unusual vaccine variants.

The level of infection is setting a new record, The hospital is overwhelmed, the government Start Introduce blockade instead of if only For those who have not been vaccinated-the picture of the fight against Covid-19 looks quite disappointing. However, there is still good news: the research team reported positive results when testing new drugs and vaccine types.

Nasal vaccine

Vaccination will remain one of the most effective tools against Covid-19. As Professor David Dockrell of the Inflammation Research Center of the University of Edinburgh told RT, “Vaccines will continue to be a core part of our virus control.”

“If we can reduce the number of infections, the severity of infections, and the extent to which the virus replicates in the human body when a person is infected, then we will slow down the ability of the virus to change and mutate,” He explained.

So I think the vaccine will still be a very important part of the prevention strategy. It is essential that no matter where people live, and regardless of the wealth of the country they live in, they can be used by all populations in the world.

However, getting vaccinated does not always mean that you have to get the shot. For example, several intranasal Covid-19 vaccines are currently being developed. When the virus enters the body through the nose, nasal sprays or drops are designed to generate a mucosal immune response and prevent it from entering the lungs.

In India, this type of vaccine has completed the second phase of clinical trials. In Russia, a nasal vaccine is undergoing clinical trials in volunteers. In Thailand, a domestic product is expected to be tested on humans next spring. In the United States, the University of Houston and Stanford University recently reported good results of their experiments on mice.

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Compared with vaccination, intranasal vaccination has many potential benefits.

“They will be easier to use because they can be self-managing. They don’t need nurses or a clinical environment,” Marcello Ferrada de Noli, professor emeritus of epidemiology in Sweden, explained to RT. Therefore, he said, he hopes to reduce the number of people who are not willing to be vaccinated. Not many of us find it a pleasure to receive a jab—after all, some people are just afraid of needles. In addition, it is much easier to vaccinate children with nasal materials.

However, what Professor de Noli is most concerned about is the duration of the vaccine’s effect. Nevertheless, scientists cannot say with certainty whether nasal materials can completely replace injections. Alexander Gintsburg, director of the Institute of Biomedical Research at the Gamaleya Center in Moscow, said that the nasal version they are studying will provide additional protection against the virus, but will not replace injections.

Bite off the virus?

The nasal vaccine is not the only vaccine being developed. This summer, it was revealed that scientists from the Russian Ministry of Defense are developing a “chewing gum” vaccine that also targets mucosal immune responses.At the same time, a British company Announce This month, it will conduct human trials on skin patches that use T cells to fight the virus. Developers hope that it will provide longer-lasting immunity than existing vaccines. The University of Queensland in Australia is working on a similar project.

Although all this seems promising, Professor de Noli warned that it will take a long time for the public to use these products. “I think the discovery in this area is a very good thing. But if we say “We have found a new type of vaccine”, people will say “Aha, so I have to wait.” But we need to vaccinate people now ,” He pointed out.

Improve Covid treatment

Unfortunately, given the low level of global immunization and the continuous emergence of new virus strains, vaccines are not a panacea. “Despite being vaccinated, people may still be infected, but I still believe that vaccine strategies will be at the core of how we manage this type of virus in the future,” Professor Dokrell said. “But we will have other very important strategies. We will have other elements. When we put them together, it gives us the best chance that people can coexist with the coronavirus, hoping that the death rate can be limited to In the much lower range that we have seen in the past 18 months.”

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Professor Dockrell explained that monoclonal antibodies will be the core of the ongoing vaccine strategy. These antibodies are similar to the antibodies the body uses to fight viruses. They are produced in the laboratory and administered by infusion or injection to enhance the patient’s response to certain diseases. Monoclonal antibody therapy is used for people at high risk of serious infections (including elderly patients over 65 years of age or patients with chronic diseases). After being approved by the FDA last year, it has been used in the United States. In early November, the European Medicines Agency recommended the authorization of two monoclonal antibody drugs.

October, AstraZeneca, UK Report The Phase 3 study of its antibody portfolio has achieved positive results. According to the developers, the combination is very effective in preventing and treating coronavirus.

Researchers are also studying the possibility of saving Covid-infected patients from the so-called “cytokine storm”-in this case, the immune system reacts so strongly that it kills not only the virus but the entire organism itself.A sort of drug This year, “Silence Storm” was registered in Russia and it has been used on patients.

Another way to fight Covid-19 is to use antiviral drugs. When the pandemic started, medical staff had to use existing drugs (such as the anti-influenza virus fapilavir) or approved drugs for emergency use (such as remdesivir). Now, more than a year has passed, and the work to create a special drug for the treatment of Covid-19 is bearing fruit. This month, Russia registered the first injectable anti-coronavirus drug.Earlier, the United Kingdom became The first country to approve antiviral pills produced by Merck and Ridgeback Biotherapeutics. Another American company, Pfizer, Got The test results of its similar drugs were positive. Both companies hope that using pills in the form of pills will make it easier to treat people at home.

Professor Denoli appreciated all the efforts made in the development of anti-coronavirus treatments. He pointed out that the key issue now is still to reduce the spread of the virus. “The new medicine is developed for people who are already sick,” He said.

But we need to prevent people from getting infected, not let them get infected, because we have some new medicines that can cure them.

The same idea has been echoed by scientists all over the world lead In a large number of articles on medical benefits: owning treatment, But no medicine can replace Vaccination is first and foremost that humans must take preventive measures and stop the pandemic.

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