Antimicrobial efficacy tends to “crippling point” resistance-FAO-Global Issues

The widespread use of antibiotics and other antimicrobial drugs has led to increasing resistance to their effectiveness.

It is estimated that 700,000 people die each year from AMR-related causes, and FAO Chief veterinary officer Keith Sumption said that if no action is taken, the annual number may soar to about 10 million by 2050.

HIV resistance

The warning is in the World Health Organization (WHO) Newest HIV resistance report According to reports, by 2020, 64% of countries with a high burden of HIV infection have formulated a national action plan to prevent, monitor and respond to HIV drug resistance.

However, the report pointed out that more and more countries are approaching the 10% resistance threshold to the drug resistance threshold before HIV treatment. When this threshold is reached, it is necessary to urgently change the first-line HIV treatment.

The report also found that People who have been exposed to antiretroviral drugs are three times more likely to resist them.

According to a recent survey conducted in 10 countries in sub-Saharan Africa, nearly half of newly diagnosed HIV-infected infants had drug-resistant HIV before starting treatment.

In addition, the report states that the number of countries achieving high levels of virus suppression has increased from 33% in 2017 to 80% in 2020.

However, it also emphasizes the need for routine viral load monitoring to deal with HIV resistance.

Keep AMR

Minimizing the spread of HIV resistance is a key aspect of the broader global antimicrobial resistance response, Who said.

Based on his PhD research in Southern Africa, Dr. Sumpton concluded that in order to reduce and control the risks of these drugs, livestock and crop producers need clear alternatives, including “good animal health and management.”

Other options are also suggested, such as enhancing animal nutrition.

“This is similar to crops,” he said. “Good soil, good genetic selection and good seeds can achieve many goals…[and] Reduce the use of antimicrobial agents in crop protection, especially rice, tomatoes and citrus”.

High-income countries can help underdeveloped countries adopt a more “progressive approach” to crop protection, while providing resources to encourage biosecurity and biosecurity at the farm level.

The use of antibiotic substitutes in feed, such as vaccinations, probiotics and prebiotics, may reduce the likelihood of AMR.

“Our goal is not to eliminate antibiotics, but to maintain their effectiveness,” said Dr. Sumption.

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